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Anti-Mouse CD18 Antibody (M18/2)

Anti-Mouse CD18 Antibody (M18/2) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD18. Anti-Mouse CD18 Antibody (M18/2) can neutralize lymphocyte function-associated antigen 1 (LFA-1) . Anti-Mouse CD18 Antibody (M18/2) can be used for the researches of immunology, such as heart transplantation[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Integrin; Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Cytoskeleton; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd18-antibody-m18-2.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD18Antibody(M18/2)]

Molecular Weight

(150 kDa)

References & Citations

[1]Zumwalde NA, et al. ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation. J Immunol. 2013 Oct 1;191 (7) :3681-93.|[2]Isobe M, et al. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science. 1992 Feb 28;255 (5048) :1125-7.|[3]Fan ST, et al. Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response. J Clin Invest. 1991 Jan;87 (1) :50-7.

Shipping Conditions

Isolate blue ice and the product with bubble pack to avoid direct contact

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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