(±) -Carnitine (chloride)

(±) -Carnitine chloride exists in two isomers, known as D and L. L-carnitine plays an essential role in the β-oxidation of fatty acids and also shows antioxidant, and anti-inflammatory activities.

Product Specifications

CAS Number

[461-05-2]

Product Name Alternative

DL-Carnitine chloride

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/__plusmn__-Carnitine_chloride.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

C[N+](C)(C)CC(O)CC(O)=O.[Cl-]

Molecular Formula

C7H16ClNO3

Molecular Weight

197.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Oyanagi E, et al. Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acidstress. Biochem Biophys Res Commun. 2011 Aug 19;412 (1) :61-7.|[2]Li J, et al. l-carnitine protects human hepatocytes from oxidative stress-induced toxicity through Akt-mediated activation of Nrf2 signaling pathway. Can J Physiol Pharmacol. 2016 May;94 (5) :517-25.|[3]Jang J, et al. l-Carnitine supplement reduces skeletal muscle atrophy induced by prolonged hindlimb suspension in rats. Appl Physiol Nutr Metab. 2016 Dec;41 (12) :1240-1247.|[4]Zambrano S, et al. L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by upregulating PPAR-γ. Am J Hypertens. 2014 Mar;27 (3) :460-70.