DNA ligase-IN-1
DNA ligase-IN-1 (Compound 1) is an inhibitor of bacterial NAD+-dependent DNA ligase (LigA) . DNA ligase-IN-1 effectively inhibits the growth of Staphylococcus aureus in vitro[1].
Product Specifications
CAS Number
68302-07-8
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dna-ligase-in-1.html
Smiles
O=C(C1=CC2=C(OC3=C(C2=O)C=CC=C3)N=C1N)N
Molecular Formula
C13H9N3O3
Molecular Weight
255.23
References & Citations
[1]Hale M R, et al. From fragments to leads: novel bacterial NAD+-dependent DNA ligase inhibitors. Tetrahedron Letters, 2015, 56 (23) : 3108-3112.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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