P53-MDM2-IN-1
P53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an Ki value of 23.35 µM. p53-MDM2-IN-1 can be used for anti-tumor research[1].
Product Specifications
CAS Number
[381717-91-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E1/E2/E3 Enzyme; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-mdm2-in-1.html
Purity
99.91
Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C1=CC=C(C=C1)C(=O)C2=C(C(=O)N(CCCN3C=CN=C3)C2C4=CC=C(C=C4)Cl)O
Molecular Formula
C23H20ClN3O3
Molecular Weight
421.88
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang W, et al. Pyrrylketone compound and application thereof as drug. China. CN102603717.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![c Maf (MAF) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI8F4]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
c Maf (MAF) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI8F4]
Recombinant Mouse MKK4/ MEK4/ MAP2K4 Protein, His-SUMO, E.coli-500ug