Escin IB

Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum) . Escin IB shows inhibitory effect on pancreatic lipase activity[1][2].

Product Specifications

CAS Number

[26339-90-2]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Lipase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/escin-ib.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC[C@]1([C@H]2OC(C)=O)[C@](CC(C)(C)[C@H]2OC(/C(C)=C\C)=O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O[C@@](O[C@H](C(O)=O)[C@@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)[C@]5(C)CO)C)[C@]3(C)-;@C[C@H]1O

Molecular Formula

C55H86O24

Molecular Weight

1131.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Abudayeh ZH, et al. Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography. Adv Pharm Bull. 2015 Nov;5 (4) :587-91.|[2]Hu JN, et al. Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae) . Chem Pharm Bull (Tokyo) . 2008 Jan;56 (1) :12-6.