Escin IB
Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum) . Escin IB shows inhibitory effect on pancreatic lipase activity[1][2].
Product Specifications
CAS Number
26339-90-2
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Lipase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/escin-ib.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@]1([C@H]2OC(C)=O)[C@](CC(C)(C)[C@H]2OC(/C(C)=C\C)=O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O[C@@](O[C@H](C(O)=O)[C@@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)[C@]5(C)CO)C)[C@]3(C)-;@C[C@H]1O
Molecular Formula
C55H86O24
Molecular Weight
1131.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Abudayeh ZH, et al. Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography. Adv Pharm Bull. 2015 Nov;5 (4) :587-91.|[2]Hu JN, et al. Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae) . Chem Pharm Bull (Tokyo) . 2008 Jan;56 (1) :12-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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