Hydrocortisone 17-butyrate
Hydrocortisone 17-butyrate is a non-fluorinated topical corticosteroid for use in psoriasis, eczema, and other inflammatory dermatoses. Hydrocortisone 17-butyrate inhibits granuloma formation in rats. Hydrocortisone 17-butyrate can induce vasoconstriction[1].
Product Specifications
CAS Number
[13609-67-1]
Product Name Alternative
Cortisol 17-butyrate; Hydrocortisone butyrate
UNSPSC
12352211
Hazard Statement
H315, H319, H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Hydrocortisone-17-butyrate.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](C(CO)=O)(OC(CCC)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
Molecular Formula
C25H36O6
Molecular Weight
432.55
Precautions
H315, H319, H320
References & Citations
[1]Brogden, R. N., et al., (1976) . Hydrocortisone 17-butyrate: a new topical corticosteroid preliminary report. Drugs, 12 (4), 249–257.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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