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SQSTM1/P62 Rabbit Polyclonal Antibody

SQSTM1 antibody, also known as ubiquitin-binding protein p62 antibody, detects the SQSTM1 protein that interacts with LC3 proteins to execute autophagosomal degradation. SQSTM1 is also reported to regulate the activation of NFκB1 downstream signaling in addition to having other cellular functions.

Product Specifications

Product Name Alternative

Sequestosome 1 , A170 , DMRV , FTDALS3 , NADGP , OSIL , PDB3 , ZIP3 , p60 , p62 , p62B

UniProt

Q13501

Reactivity

Bovine, Human, Insect, Mouse, Rat, Zebrafish

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human SQSTM1 / P62. The exact sequence is proprietary.

Target

Sequestosome 1

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cell Biology

Purification

Purified by antigen-affinity chromatography.

Concentration

0.39 mg/ml (Please refer to the vial label for the specific concentration.)

Dilution

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FCM: 1:50-1:200. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Form

Liquid

Molecular Weight

48

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Positive control: NIH-3T3 , JC , BCL-1 , PC-12 , Rat2 , Huh7 (3μM Thapsigargin 12hr), HepG2

Tested Applications

FC, ICC, IHC-P, IP, PLA, WB

Host or Source

Rabbit

Preservative

PBS, 1% rAlbumin, 20% Glycerol, 0.025% ProClin 300.

Isotype

IgG

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