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Monomethyl phthalate

Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats[1][2][3].

Product Specifications

CAS Number

[4376-18-5]

Product Name Alternative

2- (Methoxycarbonyl) benzoic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/monomethyl-phthalate.html

Purity

99.45

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(C1=CC=CC=C1C(O)=O)OC

Molecular Formula

C9H8O4

Molecular Weight

180.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189.|[2]Mathieu-Denoncourt J, et al. Chronic exposures to monomethyl phthalate in Western clawed frogs. Gen Comp Endocrinol. 2015 Aug 1;219:53-63.|[3]Zhang X, et al. Metabolite Monomethyl Phthalate (MMP) Induces Oxidative Damage in Rat Erythrocytes: Role of Vitamins C and E. Toxics. 2025 May 7;13 (5) :379.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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