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MRS8247

MRS8247 is a positive allosteric modulator (PAM) of the A3 adenosine receptor (A3AR) that can also slow the dissociation rate of agonists[1].

Product Specifications

CAS Number

2991693-72-0

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mrs8247.html

Smiles

NCCCCCCCCC#CC(C=C1)=CC=C1NC2=NC(C=CC=C3)=C3C4=C2N=C(C(CCC)CCC)N4

Molecular Formula

C33H43N5

Molecular Weight

509.73

References & Citations

[1]Pradhan B, et al. Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs) . J Med Chem. 2024 Jul 25;67 (14) :12221-12247.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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