MRS8247
MRS8247 is a positive allosteric modulator (PAM) of the A3 adenosine receptor (A3AR) that can also slow the dissociation rate of agonists[1].
Product Specifications
CAS Number
2991693-72-0
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mrs8247.html
Smiles
NCCCCCCCCC#CC(C=C1)=CC=C1NC2=NC(C=CC=C3)=C3C4=C2N=C(C(CCC)CCC)N4
Molecular Formula
C33H43N5
Molecular Weight
509.73
References & Citations
[1]Pradhan B, et al. Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs) . J Med Chem. 2024 Jul 25;67 (14) :12221-12247.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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