Brilaroxazine (hydrochloride)
Brilaroxazine (RP5063) hydrochloride is a modulator of serotonin receptors, exhibiting potential therapeutic activity in the treatment of pulmonary arterial hypertension (PAH) . Brilaroxazine hydrochloride has been shown to limit functional and structural changes associated with PAH, leading to significant improvements in pulmonary hemodynamics and right ventricular hypertrophy. Brilaroxazine hydrochloride also enhances oxygen saturation levels and alleviates elevated pulmonary arterial pressures when used as an adjunct to standard PAH therapies.
Product Specifications
CAS Number
[1708960-04-6]
Product Name Alternative
RP5063 (hydrochloride)
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/brilaroxazine-hydrochloride.html
Smiles
O=C1NC2=CC(OCCCCN3CCN(CC3)C4=C(Cl)C(Cl)=CC=C4)=CC=C2OC1.Cl
Molecular Formula
C22H26Cl3N3O3
Molecular Weight
486.82
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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