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PTEN Rabbit Polyclonal Antibody

PTEN antibody detects phosphatase and tensin homolog (PTEN), a known tumor suppressor protein with a predicted molecular weight of ~47 kDa. PTEN is a key phosphatase involved in the AKT pathway, playing important roles in cell growth, survival, and migration. Loss of PTEN function is found in various diseases, including cancers.

Product Specifications

Product Name Alternative

Phosphatase and tensin homolog , 10q23del , BZS , CWS1 , DEC , GLM2 , MHAM , MMAC1 , PTEN1 , PTENbeta , TEP1

UniProt

P60484

Reactivity

Canine, Feline, Human, Mouse, Porcine, Rat

Immunogen

Recombinant protein encompassing a sequence within the center region of human PTEN. The exact sequence is proprietary.

Target

Phosphatase and tensin homolog

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Signal Transduction

Purification

Purified by antigen-affinity chromatography.

Concentration

1.68 mg/ml (Please refer to the vial label for the specific concentration.)

Dilution

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Form

Liquid

Molecular Weight

47

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Positive control: NIH-3T3 , 293T , PC-12

Tested Applications

ICC, IHC-P, WB

Host or Source

Rabbit

Preservative

PBS, 20% Glycerol, 0.025% ProClin 300.

Isotype

IgG

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