Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Brophenexin

Product Specifications

UNSPSC Description

Brophenexin (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. Brophenexin shows neuroprotective activity. Brophenexin prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. Brophenexin protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss[1].

Target Antigen

ERK; iGluR; TRP Channel

Type

Reference compound

Related Pathways

MAPK/ERK Pathway;Membrane Transporter/Ion Channel;Neuronal Signaling;Stem Cell/Wnt

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nmdar-trpm4-in-2.html

Smiles

NCCN(CC1=CC=CC(Br)=C1)CC.[H]Cl.[H]Cl

Molecular Weight

330.09

References & Citations

[1]Yan J, et al. Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants. Science. 2020 Oct 9;370(6513):eaay3302.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139192/Brophenexin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139192/NMDAR-TRPM4-IN-2-SDS-MedChemExpress.pdf

CAS Number

2243506-33-2

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mrgpra9 (NM_001177566) Mouse Tagged ORF Clone
MG219666 10 µg

Mrgpra9 (NM_001177566) Mouse Tagged ORF Clone

Ask
View Details
ADGRL4 Antibody, FITC conjugated
A68348-100UG 100 µg

ADGRL4 Antibody, FITC conjugated

Ask
View Details
Prpsap1 (NM_026364) Mouse Untagged Clone
MC218390 10 µg

Prpsap1 (NM_026364) Mouse Untagged Clone

Ask
View Details
Mouse Monoclonal TBX1 Antibody (OTI1C2) [DyLight 350]
NBP2-74470UV 0.1 mL

Mouse Monoclonal TBX1 Antibody (OTI1C2) [DyLight 350]

Ask
View Details