KRN7000 analog 1

KRN7000 analog 1 exhibits good Th1-biased immune response through induction of interferon-γ (IFN-γ) and reduction of interleukin-4 (IL-4) . KRN7000 analog 1 is potential as an antitumor agent and vaccine adjuvant[1].

Product Specifications

UNSPSC

12352005

Target

IFNAR; Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/krn7000-analog-1.html

Smiles

OC[C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)OC[C@@H]([C@@H]([C@@H](CCCCCCCCCCCCCC)O)O)NC(CCCCCCCCCCC2=CC=C(C=C2)SC3=CC=C(C=C3)F)=O)O)O)O

Molecular Formula

C47H76FNO9S

Molecular Weight

850.17

References & Citations

[1]Hao T, et al. Stereospecific Synthesis and Biological Evaluation of KRN7000 Analogues with Thio-modifications at the Acyl Moiety[J]. ACS Medicinal Chemistry Letters, 2024.