[pTyr5] EGFR (988-993) (TFA)
Product Specifications
UNSPSC Description
[pTyr5] EGFR (988-993) TFA is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) TFA is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B)[1].
Target Antigen
Phosphatase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ptyr5-egfr-988-993-tfa.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CC(O)=O)N)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Weight
918.72
References & Citations
[1]Sarmiento M, et al. Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition. Biochemistry. 2000 Jul 18;39(28):8171-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1799A/pTyr5-EGFR-988-993-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1799A/
Clinical Information
No Development Reported
Curated Selection
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