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Argipressin (acetate)

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].

Product Specifications

CAS Number

[129979-57-3]

Product Name Alternative

Arg8-vasopressin (acetate) ; AVP (acetate)

UNSPSC

12352209

Hazard Statement

H332

Target

Apoptosis; Vasopressin Receptor

Type

Peptides

Related Pathways

Apoptosis; GPCR/G Protein

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/argipressin-acetate.html

Purity

99.16

Solubility

H2O : ≥ 100 mg/mL

Smiles

CC(O)=O.O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC1)N)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)CCC(N)=O)=O)CC(N)=O)=O)N4[C@@H](CCC4)C(N[C@@H](CCCNC(N)=N)C(NCC(N)=O)=O)=O.[x]

Molecular Formula

C46H65N15O12S2·xC2H4O2

Molecular Weight

1084.23 (free base)

Precautions

H332

References & Citations

[1]Shruti Mohan, et al. Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival. Biochimie. |[2]Thibonnier M, et al. Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells. Endocrinology. 1991 Dec;129 (6) :2845-56.|[3]Moriya T, et al. Vasopressin-induced intracellular Ca²⁺ concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Res. 2012 Nov 5;1483:1-12. |[4]Keun Suk Park, et al. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017 Jun; 70 (3) : 245–257.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

Phase 4

Available Sizes

Curated Selection

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