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BChE-IN-11

BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research[1].

Product Specifications

CAS Number

133740-30-4

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bche-in-11.html

Solubility

10 mM in DMSO

Smiles

OC1=CC(OC)=C2C3=CC=C(O)C=C3C=CC2=C1CC4=CC=C(O)C=C4

Molecular Formula

C22H18O4

Molecular Weight

346.38

References & Citations

[1]Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12 (1) :13649.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

AChE; BChE

Available Sizes

Frequently Asked Questions

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