PCSK9-IN-31
PCSK9-IN-31 (Compound WX002) is an orally active PCSK9 inhibitor. PCSK9-IN-31 can lower low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) in high cholesterol fed model rats[1].
Product Specifications
CAS Number
[2247649-76-7]
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pcsk9-in-31.html
Smiles
CC1=C(N([C@H]2CNCCC2)C(C3=CC=C(C4=NOC(C)(C)C4=O)C=C3)=O)N=CC=C1
Molecular Formula
C23H26N4O3
Molecular Weight
406.48
References & Citations
[1]Wenjie Xu, et al. CRYSTAL FORM α OF COMPOUND A, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING CRYSTAL FORM. Patent. WO2020078170A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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