PCSK9-IN-31

PCSK9-IN-31 (Compound WX002) is an orally active PCSK9 inhibitor. PCSK9-IN-31 can lower low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) in high cholesterol fed model rats[1].

Product Specifications

CAS Number

[2247649-76-7]

UNSPSC

12352005

Target

PCSK9

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pcsk9-in-31.html

Smiles

CC1=C(N([C@H]2CNCCC2)C(C3=CC=C(C4=NOC(C)(C)C4=O)C=C3)=O)N=CC=C1

Molecular Formula

C23H26N4O3

Molecular Weight

406.48

References & Citations

[1]Wenjie Xu, et al. CRYSTAL FORM α OF COMPOUND A, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING CRYSTAL FORM. Patent. WO2020078170A1.