(+) -Crinatusin A1
(+) -Crinatusin A1 (Compound (+) - 4) is a chalcone-monoterpene hybrid, which can be isolated from Cleistocalyx operculatus. (+) -Crinatusin A1 is an inhibitor for protein tyrosine phosphatase 1B (PTP1B) with IC50 of 0.9 μM. (+) -Crinatusin A1 exhibits potential as an antidiabetic agent[1].
Product Specifications
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/plus-crinatusin-a1.html
Smiles
COC1=C(C(O)=C(C(O)=C1C)C)C([C@H]2CC=C(C[C@@H]2C3=CC=CC=C3)CC/C=C(C)/C)=O
Molecular Formula
C28H34O4
Molecular Weight
434.57
References & Citations
[1]Mai VH, et al., Chalcone-Monoterpene Derivatives from the Buds of Cleistocalyx operculatus and Their Potential as Protein Tyrosine Phosphatase 1B Inhibitors. J Nat Prod. 2024 Jul 24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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