Deupirfenidone
Deupirfenidone-d3 is the deuterium labeled Pirfenidone (HY-B0673) . Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[1][2][3].
Product Specifications
CAS Number
[1093951-85-9]
Product Name Alternative
LYT-100; AMR69-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Purity
99.60
Solubility
DMSO : ≥ 100mg/mL|H2O : 12.5mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=CC=C2)C=C(C=C1)C([2H])([2H])[2H]
Molecular Formula
C12H8D3NO
Molecular Weight
188.24
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-243.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
Phase 2
Available Sizes
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