Desmethyl Levofloxacin

Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].

Product Specifications

CAS Number

[117707-40-1]

UNSPSC

12352005

Hazard Statement

H302

Target

Antibiotic; Drug Metabolite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/desmethyl-levofloxacin.html

Purity

99.77

Solubility

DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCNCC4)C(F)=CC1=C23)O

Molecular Formula

C17H18FN3O4

Molecular Weight

347.35

Precautions

H302

References & Citations

[1]Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.