TASP0412098
TASP0412098 is an orally available, potent and selective CRTH2/DP2 antagonist with high binding affinity (IC50 2.1 nM) and functional activity (IC50 12 nM) . TASP0412098 has the potential to suppress asthma in mouse and guinea pig bronchial asthma models[1].
Product Specifications
CAS Number
[1233248-29-7]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tasp0412098.html
Smiles
O=C(CC1=CN=C(C2=C1C=CC=C2)CC3=CC=C(C=C3)C(NCCC4=CC=C(C=C4)Cl)=O)O
Molecular Formula
C27H23ClN2O3
Molecular Weight
458.94
References & Citations
[1]Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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