TASP0412098
TASP0412098 is an orally available, potent and selective CRTH2/DP2 antagonist with high binding affinity (IC50 2.1 nM) and functional activity (IC50 12 nM) . TASP0412098 has the potential to suppress asthma in mouse and guinea pig bronchial asthma models[1].
Product Specifications
CAS Number
[1233248-29-7]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tasp0412098.html
Smiles
O=C(CC1=CN=C(C2=C1C=CC=C2)CC3=CC=C(C=C3)C(NCCC4=CC=C(C=C4)Cl)=O)O
Molecular Formula
C27H23ClN2O3
Molecular Weight
458.94
References & Citations
[1]Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
