Hygromycin-B kinase/HPH, E.coli (His-SUMO)

Hygromycin-B kinase/HPH Proteinas, an aminoglycoside phosphotransferase, phosphorylates and inactivates antibiotic substrates, including hygromycin and related compounds. This selective enzymatic activity highlights its specificity within the aminoglycoside class, regulating antibiotic function and potentially influencing microbial resistance mechanisms. Hygromycin-B kinase/HPH Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Hygromycin-B kinase/HPH protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

MKKPELTATS VEKFLIEKFD SVSDLMQLSE GEESRAFSFD VGGRGYVLRV NSCADGFYKD RYVYRHFASA ALPIPEVLDI GEFSESLTYC ISRRAQGVTL QDLPETELPA VLQPVAEAMD AIAAADLSQT SGFGPFGPQG IGQYTTWRDF ICAIADPHVY HWQTVMDDTV SASVAQALDE LMLWAEDCPE VRHLVHADFG SNNVLTDNGR ITAVIDWSEA MFGDSQYEVA NIFFWRPWLA CMEQQTRYFE RRHPELAGSP RLRAYMLRIG LDQLYQSLVD GNFDDAAWAQ GRCDAIVRSG AGTVGRTQIA RRSAAVWTDG CVEVLADSGN RRPSTRPRAK E