Iproplatin
Iproplatin (CHIP) is an anti-cancer agent with reduced toxicity in testicular and ovarian cancers. The major reduced product of Iproplatin by glutathione is chloro-bis (isopropylamine) glutathionatoplatinum (II) . Iproplatin is promising for research of Thrombocytopenia and a wide range of cancers[1][2].
Product Specifications
CAS Number
62928-11-4
Product Name Alternative
CHIP
UNSPSC
12352100
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/iproplatin.html
Smiles
[Cl-][Pt+4]([OH-])([OH-])([NH2]C(C)C)([NH2]C(C)C)[Cl-]
Molecular Formula
C6H20Cl2N2O2Pt
Molecular Weight
418.23
References & Citations
[1]Sessa C, et al. Phase II study of iproplatin in advanced ovarian carcinoma. J Clin Oncol. 1988 Jan;6 (1) :98-105. |[2]Volckova E, et al. Insight into the reactive form of the anticancer agent iproplatin. Eur J Med Chem. 2008 May;43 (5) :1081-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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