SNAP25 Rabbit Polyclonal Antibody
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. When cloned and expressed in E.coli, where protein palmitoylation does not occur, Cys-85, Cys-88, Cys-90 and Cys-92 in the protein sequence readily form an iron-sulfur cluster. Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Synaptosomal-associated protein 25 SNAP-25 Super protein (SUP) Synaptosomal-associated 25 kDa protein SNAP25 SNAP
Swiss Prot
P60880 Human, P60879 Mouse, P60881 Rat
Cellular Locus
Cytoplasm, perinuclear region. Cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human SNAP25 aa 1-206 / 206.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, Neuro-2a, human brain tissue, mouse brain tissue, rat brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:5,000 ;IHC-P: 1:1,000 ;FC: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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