Hupehenine (Standard)

Hupehenine (Standard) is the analytical standard of Hupehenine (HY-N0413) . This product is intended for research and analytical applications. Hupehenine is an orally active isosteroidal alkaloid that can be extracted from F. hupehensis. Hupehenine exhibits activities such as antitussive, expectorant, anticancer, and antiparasitic. In vitro, Hupehenine can also inhibit α-synuclein seeded fibril formation, making it applicable for the research of Parkinson's disease and other related disorders[1].

Product Specifications

CAS Number

[98243-57-3]

UNSPSC

12352005

Target

Apoptosis; Autophagy; Parasite; Reactive Oxygen Species (ROS) ; Reference Standards; α-synuclein

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hupehenine-standard.html

Smiles

O[C@H]1CC[C@@]2(C)[C@]([C@H](O)C[C@]3([H])[C@]2([H])C[C@]4([H])[C@@]3([H])CC[C@]5([H])[C@@]4([H])CN6[C@](CC[C@H](C)C6)([H])[C@@H]5C)([H])C1

Molecular Formula

C27H45NO2

Molecular Weight

415.65

References & Citations

[1]Wu X, et al. Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species. J Ethnopharmacol. 2018 Jan 10;210:39-46.