Anemonin
Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].
Product Specifications
CAS Number
508-44-1
Product Name Alternative
Pulsatilla camphor; Anemonine; trans-Anemonin
UNSPSC
12352005
Target
NO Synthase; PKC
Type
Natural Products
Related Pathways
Epigenetics; Immunology/Inflammation; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anemonin.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C[C@@]2([C@]3(CC2)C=CC(O3)=O)O1
Molecular Formula
C10H8O4
Molecular Weight
192.17
References & Citations
[1]Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17 (1) :39. |[2]Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116 (3) :518-27.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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