Propiomazine-d6 (hydrochloride)
Propiomazine-d6 (hydrochloride) is deuterium labeled Propiomazine (hydrochloride) . Propiomazine hydrochloride is an orally active antihistamine agent with sedative effects. Propiomazine hydrochloride can be used in the research of insomnia[1][2][3].
Product Specifications
UNSPSC
12352005
Target
Histamine Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Applications
COVID-19-immunoregulation
Field of Research
Others
Smiles
CCC(C(C=C1N2CC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C)=CC=C1SC3=C2C=CC=C3)=O.Cl
Molecular Formula
C20H19D6ClN2OS
Molecular Weight
382.98
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]B Midgren, et al. Effects of single doses of propiomazine, a phenothiazine hypnotic, on sleep and oxygenation in patients with stable chronic obstructive pulmonary disease. Respiration. 1990;57 (4) :239-42.|[3]Thunander Sundbom L, etal. Sedating antihistamines - risk of severe intoxication. Lakartidningen. 2021 Sep 30;118:21037.|[4]C.Bjerre, et al. Bioavailability of the sedative propiomazine after nasal administration in rats. International Journal of Pharmaceutics, 1996, 144 (2), 217-224.|[5]F T Serratoni, et al. Promethazine protection in carbon tetrachloride liver injury. An electron microscopic study. Arch Pathol. 1969 Jan;87 (1) :46-51.|[6]Fayez M, et al. Effect of propiomazine on plasma prolactin in the rat: counteraction by L-dopa. Proc Soc Exp Biol Med. 1985 Apr;178 (4) :606-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
C2410-01F-FITC 100 µL
CD55 (CD55 Antigen, CD55 Molecule, Complement Decay Accelerating Factor, CR, Cromer Blood Group Antigen, Cromer Blood Group System, Decay Accelerating Factor for Complement, DAF, TC) (FITC) discontinued
Sign In for Pricing
View Details BG-POR10129 1 Each
Porcine Androgen Induced Protein 1 AIG1 ELISA Kit
Sign In for Pricing
View Details 
I4131 96 Tests
Zinc finger SWIM domain-containing protein KIAA0913 (KIAA0913) Mouse ELISA Kit
Sign In for Pricing
View Details 
DZ33986-HRP 200 µL/Vial
Anti-African malaria mosquito CLIPB14 ser4 Antibody, HRP Conjugate
Sign In for Pricing
View Details