MTT5
MTT5 is a toll-like receptor 7 (TLR7) agonist. MTT5 can couple with Deruxtecan and exert anti-tumor activity in HER2 positive solid tumors through tumor cell killing and immune activation[1].
Product Specifications
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mtt5.html
Purity
98.49
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
COCCOC1=NC(N)=C2NC(N(C2=N1)CC3=CC=C(C=C3)C(N4CC5CNCC5C4)=O)=O
Molecular Formula
C22H27N7O4
Molecular Weight
453.49
References & Citations
[1]Yue H, et al. A DXd/TLR7-agonist dual-conjugate anti-HER2 ADC exerts robust anti-tumor activity through tumor cell killing and immune activation. Mol Cancer Ther. 2024 Jul 31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6329203-01 0.1 mL
OR5AS1, CT (OR5AS1, Olfactory receptor 5AS1, Olfactory receptor OR11-168) (MaxLight 550)
Sign In for Pricing
View Details MBS6329203-02 5x 0.1 mL
OR5AS1, CT (OR5AS1, Olfactory receptor 5AS1, Olfactory receptor OR11-168) (MaxLight 550)
Sign In for Pricing
View Details 
MBS1048024-01 0.02 mg (E-Coli)
Recombinant Salinispora tropica ATP synthase subunit beta (atpD)
Sign In for Pricing
View Details MBS1048024-02 0.02 mg (Yeast)
Recombinant Salinispora tropica ATP synthase subunit beta (atpD)
Sign In for Pricing
View Details