VKGILS-NH2

VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist) . VKGILS-NH2 has no effect on DNA synthesis in cells[1][2].

Product Specifications

CAS Number

[942413-05-0]

UNSPSC

12352209

Target

Protease Activated Receptor (PAR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/vkgils-nh2.html

Purity

99.33

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CCCCN)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)[C@H](C(C)C)N

Molecular Formula

C28H54N8O7

Molecular Weight

614.78

References & Citations

[1]M Tognetto, et al. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. Br J Pharmacol. 2000 Oct;131 (4) :689-94.|[2]David A Vesey, et al. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. Am J Physiol Renal Physiol. 2007 Nov;293 (5) :F1441-9.