7β-Hydroxybufalin
Product Specifications
UNSPSC Description
7β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase[1].
Target Antigen
Cholinesterase (ChE); Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/7β-hydroxybufalin.html
Solubility
10 mM in DMSO
Smiles
O[C@@]([C@@]12C)(CC[C@]1([H])C(C=C3)=COC3=O)[C@@]([C@H](C[C@]4([H])C[C@H]5O)O)([H])[C@@](CC2)([H])[C@]4(CC5)C
Molecular Weight
402.52
References & Citations
[1]Jian Xiao, et al. Bufadienolides from the Venom of <i>Bufo Bufo gargarizans</i> and Their Enzyme Inhibition Activities and Brine Shrimp Lethality. Natural Product Communications. 2018. Vol.13. No.7:827-830.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6575/7β-Hydroxybufalin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6575/
Clinical Information
No Development Reported
CAS Number
20143-97-9
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