Lodoxamide (tromethamine)
Lodoxamide tromethamine (U-42585E) is a medication for the treatment of prophylaxis of mast cell-mediated allergic disease.
Product Specifications
CAS Number
63610-09-3
Product Name Alternative
U-42585E
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Lodoxamide_tromethamine.html
Purity
99.83
Solubility
DMSO : 20 mg/mL (ultrasonic; warming) |H2O : ≥ 100 mg/mL
Smiles
N#CC1=CC(NC(C(O)=O)=O)=C(Cl)C(NC(C(O)=O)=O)=C1.OCC(CO)(N)CO.OCC(CO)(N)CO
Molecular Formula
C19H28ClN5O12
Molecular Weight
553.91
Precautions
H302, H315, H319, H335
References & Citations
[1]Watt GD, et al. Protective effect opf lodoxamide tromethamine on allergen inhalation challenge. J Allergy Clin Immunol. 1980 Oct;66 (4) :286-94.|[2]Barr ML, et al. Addition of a mast cell stabilizing compound to organ preservation solutions decreases lung reperfusion injury. J Thorac Cardiovasc Surg. 1998 Mar;115 (3) :631-6; discussion 636-7.|[3]Mann JS, et al. Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study. J Allergy Clin Immunol. 1985 Jul;76 (1) :83-90.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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