TPA-NAC
Product Specifications
UNSPSC Description
TPA-NAC is a nonfluorogenic prodrug by introducing N-acetyl-L-cysteine (NAC) into a conjugated acceptor skeleton. TPA-NAC is capable of fluorogenic selective labeling of HSA[1].
Target Antigen
Reactive Oxygen Species
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tpa-nac.html
Solubility
10 mM in H2O
Smiles
OC([C@@H](NC(C)=O)CS/C(SC[C@@H](NC(C)=O)C(O)=O)=C1C(C2=CC(C3=CC=C(N(C4=CC=CC=C4)C5=CC=CC=C5)C=C3)=CC=C2C\1=O)=O)=O
Molecular Weight
723.81
References & Citations
[1]Tianhong Wu, et al. A Rationally Designed Prodrug for the Fluorogenic Labeling of Albumin and Theranostic Effects on Drug-Induced Liver Injury. Anal Chem. 2024 Feb 16.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157779/TPA-NAC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157779/
Clinical Information
No Development Reported
Curated Selection
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