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Mizoribine (Standard)

Mizoribine (Standard) is the analytical standard of Mizoribine. This product is intended for research and analytical applications. Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC50 of approximately 100 μM for anti-HCV activity. Immunosuppressant[1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively[2].

Product Specifications

CAS Number

50924-49-7

Product Name Alternative

NSC 289637 (Standard) ; HE 69 (Standard)

UNSPSC

12352005

Target

Antibiotic; HCV; Parasite; Reference Standards; SARS-CoV

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mizoribine-standard.html

Purity

99.93

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(O)=C(C(N)=O)N=C2)O1

Molecular Formula

C9H13N3O6

Molecular Weight

259.22

References & Citations

[1]Naka K, et al. Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha. Biochem Biophys Res Commun. 2005 May 13;330 (3) :871-9.|[2]Saijo M, et al. Inhibitory effect of Mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS) -associated coronavirus. Antiviral Res. 2005 Jun;66 (2-3) :159-63.|[3]Kamada H, et al. Effect of Mizoribine on collagen-induced arthritis in mice. Jpn J Pharmacol. 1996 Feb;70 (2) :169-75.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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