Purotoxin 1
Purotoxin 1 is a P2X3 receptor inhibitor. Purotoxin 1 shows antinociceptive properties in animal models of inflammatory pain. Purotoxin 1 can be isolated from the venom of the wolf spider Geolycosa sp[1].
Product Specifications
CAS Number
1396322-38-5
UNSPSC
12352209
Target
P2X Receptor
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/purotoxin-1.html
Solubility
10 mM in DMSO
Smiles
O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC3=CNC=N3)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(O)=O)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H]5CC(N)=O)=O)CC6=CC=C(O)C=C6)=O)=O)CO)=O)C)=O)CC(N)=O)=O)CSSC[C@H](NC5=O)C(N[C@H]2C(C)C)=O)=O)CCCCN)=O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCC(O)=O)=O)C)=O)CSSC[C@H](NC1=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H]4CCCCN)=O)CC(C)C)=O)=O)[C@@H](C)O)=O)=O)CC7=CC=C(O)C=C7
Molecular Formula
C155H249N51O47S8
Molecular Weight
3835.47
References & Citations
[1]Grishin EV, et al. Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain. Ann Neurol. 2010 May;67 (5) :680-3.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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