6-Azuridine
6-Azuridine (6-Azauridine) is an orally active purine nucleoside analogue. 6-Azuridine activates autophagic flux, induces Apoptosis that depends on AMPK and p53. 6-Azuridine exhibit both antitumor and antiviral activities[1][2][3][4][5][6].
Product Specifications
CAS Number
54-25-1
Product Name Alternative
6-Azauridine
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H351
Target
AMPK; Apoptosis; Autophagy; MDM-2/p53; Nucleoside Antimetabolite/Analog; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Others
Assay Protocol
https://www.medchemexpress.com/6-azuridine.html
Purity
99.83
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(N1)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)N=CC1=O
Molecular Formula
C8H11N3O6
Molecular Weight
245.19
Precautions
H302+H312+H332, H351
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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