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L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride)

L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

2483829-89-4

UNSPSC

12352211

Target

Isotope-Labeled Compounds; PROTAC Linkers

Type

Isotope-Labeled Compounds

Related Pathways

Others; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/l-azidohomoalanine-1-2-3-4-13c4-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

[N-]=[N+]=[15N][13CH2][13CH2][13C@H]([15NH2])[13C](O)=O.Cl

Molecular Formula

13C4H9ClN2 15N2O2

Molecular Weight

186.55

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

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