L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride)
Product Specifications
UNSPSC Description
L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
Isotope-Labeled Compounds; PROTAC Linkers
Type
Isotope-Labeled Compounds
Related Pathways
Others;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/l-azidohomoalanine-1-2-3-4-13c4-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=[15N][13CH2][13CH2][13C@H]([15NH2])[13C](O)=O.Cl
Molecular Weight
186.55
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140346AS/L-Azidohomoalanine-1-2-3-4-13C4-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140346AS/
Clinical Information
No Development Reported
CAS Number
2483829-89-4
Available Sizes
Curated Selection
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