7,3′,5′-Trihydroxyflavanone

7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, induces the apoptotic cell death of MCF-7 cells by increasing Bax expression level. 7,3′,5′-Trihydroxyflavanone also exhibits antioxidant activity[1][2].

Product Specifications

CAS Number

[847375-46-6]

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7-3-5-trihydroxyflavanone.html

Solubility

10 mM in DMSO

Smiles

O=C1C[C@@H](C2=CC(O)=CC(O)=C2)OC3=CC(O)=CC=C13

Molecular Formula

C15H12O5

Molecular Weight

272.25

References & Citations

[1]Abdullah H, et, al. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int. 2010 May 4;10:14.|[2]Tsvetkov DE, et, al. Components of the extracts of the knot wood of Dalbergia Sissoo Linn. and their antioxidant activity. Russian Chemical Bulletin. 2019 Sep; 68:1756-1762.