7,3′,5′-Trihydroxyflavanone
Product Specifications
UNSPSC Description
7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, induces the apoptotic cell death of MCF-7 cells by increasing Bax expression level. 7,3′,5′-Trihydroxyflavanone also exhibits antioxidant activity[1][2].
Target Antigen
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7-3-5-trihydroxyflavanone.html
Solubility
10 mM in DMSO
Smiles
O=C1C[C@@H](C2=CC(O)=CC(O)=C2)OC3=CC(O)=CC=C13
Molecular Weight
272.25
References & Citations
[1]Abdullah H, et, al. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int. 2010 May 4;10:14.|[2]Tsvetkov DE, et, al. Components of the extracts of the knot wood of Dalbergia Sissoo Linn. and their antioxidant activity. Russian Chemical Bulletin. 2019 Sep; 68:1756-1762.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N9391/7-3-5-Trihydroxyflavanone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9391/
Clinical Information
No Development Reported
CAS Number
847375-46-6
Available Sizes
Curated Selection
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