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SYHA1813

SYHA1813 is a dual inhibitor of CSF1R and VEGFR. SYHA1813 has potent antitumor activity against GBM[1].

Product Specifications

CAS Number

1807466-30-3

UNSPSC

12352005

Target

C-Fms; VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/syha1813.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NNC2=C1C(C3=CC=C4C(C=CC=C4C(NC5=CC=C(F)C(C)=C5)=O)=C3)=CC=C2

Molecular Formula

C25H19FN4O

Molecular Weight

410.44

References & Citations

[1]Yingqiang Liu, et al. Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma. Acta Pharm Sin B. 2023, 13,12.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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