C12-113
C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice[1][2].
Product Specifications
CAS Number
[1220890-27-6]
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c12-113.html
Concentration
29.26 mM * 40 μL in Ethanol
Purity
98.6
Solubility
10 mM in DMSO
Smiles
OC(CCCCCCCCCC)CN(CC(CCCCCCCCCC)O)CCN(CCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)C
Molecular Formula
C53H111N3O4
Molecular Weight
854.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Li J, Song J S, et al. YY1 regulates melanocyte development and function by cooperating with MITF[J]. PLoS genetics, 2012, 8 (5) : e1002688.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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