Pyridoxine (hydrochloride)

Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

Product Specifications

CAS Number

[58-56-0]

Product Name Alternative

Vitamin B6 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H318, H402

Target

Endogenous Metabolite; Keap1-Nrf2

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Pyridoxine_hydrochloride.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : ≥ 50 mg/mL|H2O : ≥ 50 mg/mL

Smiles

OCC1=C(CO)C(O)=C(C)N=C1.Cl

Molecular Formula

C8H12ClNO3

Molecular Weight

205.64

Precautions

H318, H402

References & Citations

[1]Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand) . 2018 Jul 30;64 (10) :119-124.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Citation 01

Dev Cell. 2025 Nov 27:S1534-5807 (25) 00691-4.|Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.|Nature. 2025 Jul;643 (8070) :192-200.|Cancer Lett. 2020 Nov 1;492:96-105.|Microbiome. 2019 Mar 20;7 (1) :43. |Molecules. 2023 Apr 11;28 (8) :3375.|Nat Commun. 2020 Feb 18;11 (1) :941.