ADPRP
ADPRP is an intranuclear enzyme whose main activity is to use NAD+ (nicotinamide adenine dinucleotide) as a substrate to add ADP-ribose units to chromatin-bound proteins, including the ADPRP enzyme itself. This process, called poly (ADP-ribosylation), is a post-translational modification that regulates the interaction between DNA and nuclear proteins[1].
Product Specifications
CAS Number
53595-18-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H332
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/adprp.html
Smiles
O[C@H]1[C@@H](OP(O)(O)=O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OC[C@H]4OC(O)[C@H](O)[C@@H]4O)(O)=O)(O)=O
Molecular Formula
C15H24N5O17P3
Molecular Weight
639.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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