HSD17B13-IN-80-d2
HSD17B13-IN-80-d2 (Compound 200) is the the deuterium labeled HSD17B13-IN-80. HSD17B13-IN-80 is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-80 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI).
Product Specifications
CAS Number
2770247-90-8
UNSPSC
12352005
Target
17β-HSD
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
OC1=C(Cl)C=C(C(NC2=C3C(N=C(C)N(C(C4=CC=CC=C4C(F)(F)F)([2H])[2H])C3=O)=C(C)C=C2)=O)C=C1Cl
Molecular Formula
C25H16D2Cl2F3N3O3
Molecular Weight
538.34
References & Citations
[1]Sampath Kumar Anandan, et al. Dichlorophenol hsd17b13 inhibitors and uses thereof. WO2022103960A1. 2022-05-19.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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