C108297
C108297 is a selective glucocorticoid receptor (GR) modulator (GR binding Ki 0.7 nM; GR reporter gene functional Ki 0.6 nM) . C108297 attenuates obesity by reducing caloric intake and increasing lipolysis and fat oxidation, and in addition attenuates inflammation[1][2].
Product Specifications
CAS Number
864972-30-5
UNSPSC
12352005
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c108297.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COCCOC[C@]12CC3=C(C=C1CCN(C2)S(=O)(C4=CC=C(C=C4)C(C)(C)C)=O)N(N=C3)C5=CC=C(C=C5)F
Molecular Formula
C30H36FN3O4S
Molecular Weight
553.69
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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