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Catechin

Product Specifications

UNSPSC Description

Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

Target Antigen

Apoptosis; COX; Endogenous Metabolite; Influenza Virus

Type

Natural Products

Related Pathways

Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Catechin.html

Purity

99.57

Solubility

DMSO : 100 mg/mL (ultrasonic)|H2O : 12.5 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C3C1

Molecular Weight

290.271

References & Citations

[1]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9.|[2]Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.|[3]Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259.ACS Omega. 2024 May 17.|Acta Pharm Sin B. 2021 Jan;11(1):143-155.|Antioxidants (Basel). 2024 Jul 28;13(8):909.|Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.|Biochem Biophys Res Commun. 2023 Dec 20, 687, 149196.|Biomaterials. 2021, 120952.|Int J Insect Sci. 2018 Feb 28;10:1179543318758409.|Plant Cell Physiol. 2020 Feb 1;61(2):318-330.|Plants. 2021, 10(11), 2525.|SSRN. 2023 Jul 14.|Toxicol Appl Pharmacol. 2024 Jul 14:490:117036.|Autophagy. 2021 Apr;17(4):872-887.|Phytomedicine. 2024 May 12:130:155733.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0898/Catechin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0898/Catechin-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

154-23-4

Available Sizes

Curated Selection

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