Catechin
Catechin ((+) -Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
Product Specifications
CAS Number
154-23-4
Product Name Alternative
(+) -Catechin; Cianidanol; Catechuic acid
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; COX; Endogenous Metabolite; Influenza Virus
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Catechin.html
Purity
99.57
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C3C1
Molecular Formula
C15H14O6
Molecular Weight
290.27
Precautions
H315, H319, H335
References & Citations
[1]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40 (2) :173-9.|[2]Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.|[3]Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70 (1) :245-259.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
COX-1
Citation 01
ACS Omega. 2024 May 17.|Acta Pharm Sin B. 2021 Jan;11 (1) :143-155.|Antioxidants (Basel) . 2024 Jul 28;13 (8) :909.|Biochem Biophys Res Commun. 2018 Sep 3;503 (1) :297-303.|Biochem Biophys Res Commun. 2023 Dec 20:687:149196.|Biomaterials. 2021 Aug:275:120952.|Biomed Chromatogr. 2025 Nov;39 (11) :e70225.|Cancer Rep (Hoboken) . 2025 May;8 (5) :e70169.|Cell Death Dis. 2024 Dec 26;15 (12) :932.|Food Res Int. 2025 Oct:218:116882.|Int J Insect Sci. 2018 Feb 28:10:1179543318758409.|Phytomedicine. 2025 May:140:156549.|Plant Cell Physiol. 2020 Feb 1;61 (2) :318-330.|Plants. 2021 Nov 20;10 (11) :2525.|Rapid Commun Mass Spectrom. 2025 Dec 15;39 (23) :e10134.|SSRN. 2023 Jul 14.|Toxicol Appl Pharmacol. 2024 Jul 14:490:117036.|Autophagy. 2021 Apr;17 (4) :872-887.|Phytomedicine. 2024 May 12:130:155733.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2850274 100 µL
Ghrelin Receptor Rabbit pAb, IRDye 800CW conjugated
Sign In for Pricing
View Details 
