Rolapitant (Standard)
Rolapitant (Standard) is the analytical standard of Rolapitant. This product is intended for research and analytical applications. Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model[1][2].
Product Specifications
CAS Number
552292-08-7
Product Name Alternative
SCH619734 (Standard)
UNSPSC
12352005
Target
Neurokinin Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rolapitant-standard.html
Smiles
C[C@@](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)([H])OC[C@@]2(C3=CC=CC=C3)CC[C@@](CCC4=O)(N4)CN2
Molecular Formula
C25H26F6N2O2
Molecular Weight
500.48
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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