Urdamycin A

Urdamycin A (Compound 3b) is an angucycline antibiotic that can be isolated from Streptomyces fradiae. Urdamycin A is an orange indicator with a change of the color to ultramarine blue at pH 7.7. Urdamycin A has anticancer activity with IC50s of 2.4 and 0.55 μg/mL in proliferation and stem cell assays, respectively[1].

Product Specifications

CAS Number

[98474-21-6]

UNSPSC

12171500

Target

Antibiotic; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Anti-infection; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/urdamycin-a.html

Purity

88.2

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(O)C([C@H]2C[C@H]([C@@H]([C@H](O2)C)O)O[C@@H]3O[C@H]([C@H](CC3)O[C@H]4C[C@H]([C@@H]([C@H](O4)C)O)O)C)=CC=C1C5=O)C(C=C[C@@]6(C[C@@](O)(CC7=O)C)O)=C5[C@]67O[C@@H]8O[C@H]([C@H](CC8)O)C

Molecular Formula

C43H56O17

Molecular Weight

844.89

References & Citations

[1]Drautz H, et al. Metabolic products of microorganisms. 234. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. I. Isolation, characterization and biological properties. J Antibiot (Tokyo) . 1986 Dec;39 (12) :1657-69.