CYP1B1-IN-4
Product Specifications
UNSPSC Description
CYP1B1-IN-4 is a 2,4-diarylthiazole compound with selectively CYP1B1 inhibition (IC50=0.2 nM). CYP1B1-IN-4 has little cytotoxicity and high stability in both human and rat liver microsomes[1].
Target Antigen
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyp1b1-in-4.html
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C(OC)=C1)C2=NC(C3=CC=C(C=C3)C#N)=CS2
Molecular Weight
322.38
References & Citations
[1]Hachey AC, et al. Design of Cytochrome P450 1B1 Inhibitors via a Scaffold-Hopping Approach. J Med Chem. 2022 Dec 15.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152118/CYP1B1-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152118/CYP1B1-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2685779-55-7
Available Sizes
Curated Selection
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